DNA mismatch repair is a cellular mechanism that recognizes and repairs errors (e.g., insertions and deletions) in the DNA sequence. Mismatch repair occurs during DNA replication and recombination.
- Mismatch repair of DNA might be viewed as a race between an endonuclease and METHYLASE.
- Methylases are enzymes that catalyze the addition of a methyl group to cytosine (C) and Adenine (A) nitrogenous bases.
- This modification (methylation) protects the DNA sequence from the action of endonucleases that cut the DNA sequence during mismatch repair.
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