How can one hormone, such as estrogen, mediate so many effects?

A. Estrogen binds to common receptors inside several cell types, and each cell responds in the same way to its binding
B. Estrogen binds to specific receptors inside many kinds of cells, each of which has different responses to its binding
C. Estrogen is produced in high concentrations by a large number of different cell types
D. Estrogen does not affect cells that lack estrogen receptors in the cell membrane