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The citrate synthase, isocitrate dehydrogenase, and the α-ketoglutarate dehydrogenase complex are the three key control points.

What are the key control points within the citric acid cycle?

The key control points in citric acid cycle are the reactions catalyzed by citrate synthase, isocitrate dehydrogenase, and the α-ketoglutarate dehydrogenase complex.

So we can conclude that citrate synthase, isocitrate dehydrogenase, and the α-ketoglutarate dehydrogenase complex are the three key control points.

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The citric acid cycle is a chemical cycle that releases stored energy.  Citrate synthase, isocitrate dehydrogenase, and alpha-ketoglutarate dehydrogenase are the control point of the cycle.

What is a citric acid cycle?

The citric acid cycle or the TCA cycle (tricarboxylic acid cycle) is the chemical series of reactions that releases energy from food sources like fats, carbohydrates, and proteins.

The TCA cycle includes enzymes and many substances that regulate it but three major points are Citrate synthase, isocitrate dehydrogenase, and alpha-ketoglutarate dehydrogenase.

Therefore, they get inhibited, regulated, and limit the rate of the reaction.

Learn more about the citric acid cycle here:

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