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Two possible causes of metabolic acidosis include diarrhea and diabetes.

Metabolic acidosis is a condition in which too much acid is produced in the body. However, it may also occur when the kidneys cannot remove sufficient amount of acid from the body. There are several types of metabolic acidosis:

  • Diabetic acidosis (also known as diabetic ketoacidosis or DKA) develops when substances called ketone bodies (acidic in nature) build up during uncontrolled diabetes (usually type 1 diabetes).
  • Hyperchloremic acidosis is caused due to the loss of a large amount of sodium bicarbonate from the body, which usually results from severe diarrhea.
  • Kidney diseases such as uremia, distal renal tubular acidosis or proximal renal tubular acidosis.
  • Lactic acidosis which results from a buildup of lactic acid.
  • Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanol.
  • Severe dehydration.

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