Respuesta :
Non-coding RNAs are a large family of RNAs that are not coding for known proteins.
microRNAs(miRNA):
- MicroRNAs are 18–24 nucleotide short RNA transcripts that control translational gene expression.
- The majority of miRNAs are synthesized from DNA sequences into precursor miRNAs (pre-miRNAs), main miRNAs (pri-miRNAs), and mature miRNAs.
- miRNAs interact with the 3′ UTR of target mRNAs to suppress expression.
Small nuclear RNAs(snRNA):
- The typical length of a snRNA is 150 nucleotides.
- snRNAs are found in eukaryotic cells in the Cajal bodies and splicing speckles of the cell nucleus. Either RNA polymerase II or RNA polymerase III transcribes them.
Long noncoding RNAs(lncRNA):
- The three domains of the lncRNA are structured into a modular structure with 12 helices, 8 terminal loops, 5 sizable internal loops, and a five-way junction.
- lncRNA are epigenetic regulators by modulating histone or DNA modification, primarily methylation and acetylation, and control epigenetic modification primarily in the nucleus, which controls gene transcription at the transcriptional level.
- They regulate cellular processes by (i)chromatin remodeling, (ii) preventing the activity of particular transcription factors, (iii), blocking the promoter area of particular genes, (iv), building double-stranded RNA complexes with mRNA or miRNAs, and finally causing gene expression.
Learn more about the Types of RNA with the help of the given link:
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