Confounding variable is extra variable that affect the other variable in a way that produces spurious or distorted associations between two variable.
The total score is calculated by finding the sum of 20 times.The confound the true relationship between two variables. There are some factor other than the one being studied that is associated both with the disease and with the factor being studied like independent variables.
Hamilton rating scale for depression to measure depression in individual.There are some ways to identify compute the measure of association both before and after adjusting for a potential confounding factor.10% difference between the two measures or then confounding was present.
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