A person with type B- blood receives a transfusion of type O+ blood. It is his very first blood transfusion. Will there be a transfusion reaction? Why or why not? No: the recipient has no antibodies to the Rh factor because this is his first transfusion. Yes: the recipient has anti-Rh antibodies which will clump and hemolyze the donated blood. Yes: the recipient must receive blood of the same type as his or her own. Yes: the anti-A antibodies of the recipient will clump and hemolyze the donated blood.