During the signal transduction process, the signal often triggers a signal transduction cascade. For example, an activated receptor activates hundreds of protein A. Each activated protein A activates hundreds of protein B and so on until a cellular response occurs. What purpose does this cascade serve? The cascade serves to amplify the signal, so one activated receptor can have a significant response. Having several intermediates allows for the cell to determine what signals it will sense. Having a cascade allows the cell to respond to different signals. The cascade makes signaling easier to shut off or terminate.