During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid. The dissociation of lactic acid to lactate is shown in the reaction below. Lactic acid has a pKa of 3.86.
A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.05. Calculate the ratio of the lactate concentration to the lactic acid concentration in this solution.
What fraction of the lactic acid/lactate mixture is lactic acid?

Respuesta :

Answer:

The answer to this problem is the lactate to lactic acid ratio is  approximately 7:1. , for detailed steps on how to go about the answer, please see below

Explanation:

From the question. pH of the solution =3.05

pH being the concentration of [H3O+] in the solution, [H3O+] can be calculated by

pH=−log10[H3O+]  hence [H3O+]= [tex]10^{-pH}[/tex]

which is = [tex]10^{-3.05}[/tex] = 8.91×[tex]10^{-4}[/tex]mol×dm−3

That is the concentration of H3O+, [H3O+] is approximatley 8.91×[tex]10^{-4}[/tex]mol×dm−3 as

When lactic acid dissociates, it forms one oxonium ion,[H3O+], and one lacate ion that is there are equal number of moles of oxonium ion and lacate ion in the solution hence  [H3O+]=[lactate]

The Ka of the lactic cid can be found by pKa = -LogKa

or Ka = [tex]10^{-pKa}[/tex] = [tex]10^{-3.86}[/tex] = 1.34 × [tex]10^{-4}[/tex]mol×dm−3

The Ka equation is given by

Ka=[tex]\frac{[H3O+][lactate]}{[Lactic.]}[/tex]

Since the concentration of the oxonium ion and the lactate ion are equal

[H3O+]=[lactate]

we have

(1.34 × [tex]10^{-4}[/tex])=(8.91×[tex]10^{-4}[/tex])²÷ x

where x = lactic acid concentration

Hence

x=[Lactic]=(8.91×[tex]10^{-4}[/tex])² ÷ (1.34 × [tex]10^{-4}[/tex]) =5.92×10^(-3)

Therefore the

[Lactate]/[Lactic]=5.92×10^(-3)/8.91×[tex]10^{-4}[/tex]≈6.65 ≈ 7

The concentration of lactate is approximately 7 times higher than the concentration of lactic acid, therefore the lactate to lactic acid ratio is  approximately 7:1.