One manifestation of physical dependence is changes in normal bodily function.
Physical dependence is a psychological term that refers to an impairment in the normal functioning of the body.
In other words, physical dependence is a condition characterized by the alteration of the body's functions as a result of the suspension or reduction of the dose of a drug or substance that the patient has taken for a long time.
According to the above, the sentence that best completes the statement is changes in normal bodily functions because it states the phenomena experienced by a person who suffers from physical dependence.
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