Small single-stranded RNA molecules called microRNAs (miRNAs) are capable of base pairing with specific binding sites in the 3′ untranslated region of many mRNA transcripts. Transcription of gene Q yields an mRNA transcript that contains such an miRNA binding site, which can associate with miRNA‑delta, a specific miRNA molecule.

Which of the following best supports the claim that binding of miRNA‑delta to the miRNA binding site inhibits translation of gene Q mRNA?

When the promoter for gene Q is altered, transcription is inhibited.

A.Translation of Q mRNA is inhibited regardless of whether the miRNA binding site sequence is altered.

B.Translation of Q mRNA is inhibited in the absence of miRNA‑delta.

C.When the miRNA binding site sequence is altered, translation of Q mRNA occurs in the presence of miRNA-delta.

The answer choice before A mentions transcription, and the question is concerning translation, so that choice is incorrect. The A you put is also incorrect because anytime a binding site is altered for miRNA it won’t be able to inhibit translation as it should. It suggests that miRNA-delta doesn’t need to directly interact with Q mRNA to inhibit. B is also incorrect because it is suggesting that binding of miRNA-delta is not required for inhibition, which refutes the claim. This leaves C as the correct answer.

kasliwalalvi24 kasliwalalvi24 · Answer 2 · 2022-01-11T08:15:38+01:00

What is microRNA?

microRNA is a small class of non-coding RNAs, which plays a crucial role in the regulation of gene expression. These RNAs are capable of base pairing at 3' untranslated region of mRNA transcripts.

When the miRNA binding site sequence is altered, translation of Q mRNA occurs in the presence of miRNA-delta. MiRNAs are responsible for negatively regulating the expression of many genes. These small guides can affect the translation by altering the mRNA cap structure and poly-A tail.

The answer can be explained as:

Option A mentions that the translation of Q mRNA is inhibited which will alter the miRNA binding sequence. Thus, the altered sequence won't be able to inhibit the translation.

Option B explained the binding of miRNA-delta is not required for inhibition, which is stated wrongly upon the given process of translation.

Option C best describes that when the miRNA sequence is altered, the translation of Q mRNA occurs in the presence of miRNA-delta.

Thus, the correct answer is Option C.

To know more about translation, refer to the following link:

https://brainly.com/question/17485121