prokaryotic cells are small in size (<5um). eukaryotic cells are larger (>10um). prokaryotic cells are always unicellular, whereas eukaryotic cells are often multicellular. prokaryotic cells have no nucleus or any otber membrane bound organelles such as mitochondria, and eukaryotic cells always have a nucleus and other membrane bound organelles. prokaryotic DNA is circular without proteins and eukaryotic DNA is linear and is associated with proteins to form chromatin. prokaryotic cells have small ribosomes and eukaryotic cells have large ribosomes. prokaryotic cells have no cytoskeleton but eukaryotic cells do. prokaryotic cells are mostly rigid by rotating flagellum (made of flagelin) and eukaryotic cells are mostly flexible by waving cilia or flagella (made of tubulin). prokaryotic crlls division is by binary fission and is always asexual, and eukaryotic is meiosis or mitosis and is asexual or sexual. prokaryotic cells have a huge variety of metabolic pathways, but eukaryotic cells have only common metabolic pathways
