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What distinguishes a substance from a mixture? Mixtures can be separated physically, while compounds cannot. Samples of the same substance can have different intensive properties. Substances are compounds, and mixtures are not. Mixtures are groupings of elements, and compounds are not.

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Answer Mixtures are physically combined structures that can be separated into their original components. A chemical substance is composed of one type of atom or molecule. A mixture is composed of different types of atoms or molecules that are not chemically bonded.

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