There is a practical joker in the maternity ward who removed all the baby ID bracelets. There are two babies that cannot be easily distinguished, and the parents want to be sure they get the right ones back, so the doctors do a blood test.
Parents 1: mom is heterozygous type A and the dad is type O. Parents 2: mom is heterozygous type A and dad has AB. The baby 1 has blood type AB and baby 2 has blood type O.
Determine what baby goes with which parents. Explain how you know. Provide evidence and reasoning by explaining multiple alleles inheritance and your Punnett squares results.

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Answer:

Baby 1 goes to parent 2 and baby 2 goes to parent 1. My results for the first Punnett square for parent 1 was 100% AO. My results for the second Punnett square is 50% AO, 50% OO. My results for the first punnett squares for parent 2 is 50% AA, 50% AB, and the results for the second punnett square is 25% AA, 25% AO, 25% AB, 25% BO.

Explanation:

Baby 1 belongs to parents 2, whereas baby 2 belongs to parents 1.

In this case, it is important to have into account that the ABO blood type is inherited in an autosomal codominant fashion.

The A and alleles B are codominant and therefore both alleles are expressed, thereby if an individual inherits allele A from one parent and allele B from another parent, he/she has blood type AB. It is the case for baby 1 (genotype AB).

Conversely, the A and B alleles are dominant on the allele O, which is recessive. It is the case for baby 2 (genotype OO).

The genotypes of the parents are:

Parents 1:

  • Mom is heterozygous type A (genotype AO) and the dad is type O (genotype OO).

Parents 2:

  • Mom is heterozygous type A (genotype AO) and dad has AB (genotype AB).

Parents 2 can produce these gametes:

  • Mom: 1/2 A; 1/2 O
  • Dad: 1/1 O

So their offspring can be:

          A       O

O      AO    OO

F1: 1/2 AO; 1/2 OO

In consequence, baby 2 (genotype OO) belongs to parents 1

Parents 2 can produce these gametes:

  • Mom: 1/2 A; 1/2 O
  • Dad: 1/2 A; 1/2 B

So their offspring can be:

          A       O

A      AA     AO

B     AB     BO

F1: 1/4 AA; 1/4 AO; 1/4 AB; 1/4 BO

In consequence, baby 1 (genotype AB) belongs to parents 2

In conclusion, baby 1 belongs to parents 2, whereas baby 2 belongs to parents 1.

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