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Answer:

When calcium concentration increases during depolarization, it shifts the conformation of troponin and tropomyosin, and actin is able to associate with myosin. As calcium is taken up again by the sarcoplasmic reticulum the muscle cell relaxes.

The effect that can be associated with increase in concentration of calcium ion in the sarcoplasm is :

Changing of shape and position of tropomyosin.

Can also cause muscles stiffness.

  • When the Ca2+ concentration become high in the sarcoplasm, there would be change in the position of tropomyosin as result of the binding effect of Ca2+ binds on troponin.

  • Then the tropomyosin will be moved away from myosin binding sites on actin, then a cross bridge will be formed

However, the effect if this on muscles is muscles stiffness.

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