Explanation:
Since the unit conversion from pounds (lbs) to kilograms (kg) follows the relation
[tex]1 \ \text{lb} \ \approx \ 0.45359 \ \text{kg}[/tex],
Using dimensional analysis, the correct dosage in units of mililitres is
[tex]\text{Dosage} \ = \ 450 \ \text{lb} \ \times \ \displaystyle\frac{0.45359 \ \text{kg}}{1 \ \text{lb}} \ \times \ \displaystyle\frac{22,000 \ \text{IU}}{1 \ \text{kg}} \ \times \ \displaystyle\frac{1 \ \text{mL}}{500,000 \ \text{IU}} \\ \\ \text{Dosage} \ = \ 8.9 \ \text{mL} \ \ \ \ \ \ (1 \ \text{d.p.})[/tex].
