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Fine needle aspiration biopsy (FNA) would be the most appropriate initial investigation for thyroid nodules.

What are Thyroid Nodules?

Thyroid nodules may be defined as a condition of an overgrowth of normal thyroid tissue due to some unknown facts and circumstances.

Fine needle aspiration biopsy (FNA) would be considered the most standard test for evaluating or investigating thyroid nodules.

It is a head strategy, accomplished beneath no or regional anesthesia with a 23 to 27-gauge needle, to acquire tissue specimens for cytological examination.

Therefore, it is well described above.

To learn more about Thyroid Nodules, refer to the link:

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