The environment that a pathogen would encounter in the small intestine would be harsh and unfavorable for its existence.
The small intestine has a harsh environment for microbial life on account of short transit time, the influx of digestive enzymes as well as bile and intermittent food substrate delivery.
The intestinal microbiota is the collective term used to describe the large and diverse microbial community that inhabits the intestine.
An important benefit provided by the intestinal microbiota to the host intestine is the protection from colonization by exogenous pathogens (a phenomenon nowadays termed as colonization resistance) and from overgrowth of indigenous pathobionts i.e. potential pathogenic symbionts of the microbiota.
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