Adenyl cyclase is the enzyme would you expect to have increased activity in response to a higher than normal concentration of epinephrine. As epinephrine levels rise, adenylyl cyclase is activated in muscle cells, increasing glycogenolysis.
The glucose-6-phosphate produced by glycogenolysis is utilised directly in glycolysis since it cannot be converted into free glucose and expelled from the muscle cell. Adenylyl cyclase is activated once epinephrine attaches to its receptor on the target cell and after the energy-rich molecule adenosine triphosphate, or ATP, is hydrolyzed to produce cAMP.
The phosphate creates two bonds to the adenine base in cAMP, a new form of adenosine monophosphate (AMP).
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