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Emphysema can lead to respiratory acidosis acid/base disturbance.The compensated respiratory acidosis is typically the result of the chronic condition  , the slow nature of onset giving the kidney time to compensate.

If the primary acid-base disorder is from respiratory , then the kidneys will compensate. If the primary acid-base disorder is from metabolic cause, then the lungs will compensate.The respiratory compensation can be begin within minutes and becomes maximal in 12-24 hours

The respiratory acidosis occurs when breathing out does not get of enough [tex]CO_{2}[/tex] . The increased [tex]CO_{2}[/tex] that  remains results in overly acidic blood. This can results from respiratory problems.

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