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A salicylate is contraindicated in patients who have had surgery within the past week the reason is -

Salicylates have been derived from the willow tree bark. The Sumerians had been cited to have used treatments derived from the willow tree for pain management as far returned as 4000 years ago. Hippocrates used it for dealing with ache and fever. He even utilized tea brewed from it for ache management all through childbirth.

In a 1763 medical trial, the first of its kind, Reverend Edward Stone studied the consequences of willow bark powder for treating fever. approximately a hundred years later, the consequences of the willow bark powder have been studied for acute rheumatism.

In 1828, Professor Johann Buchner used salicin, the Latin word for willow. Henri Leroux used it to deal with rheumatism after isolating it in a crystalline shape in 1829. in the 1800s, the Heyden Chemical organization was the primary to mass-produce salicylic acid commercially Salicylates. It turned into no longer until 1899 when a modified model named acetylsalicylic acid was registered and marketed by way of Bayer underneath the alternate name aspirin.

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