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Membrane-type frizzled-related protein regulates lipidome and transcription for photoreceptor retaining docosahexaenoic acid (DHA)  function.

  • Frizzled proteins function as receptors for secreted Wnt proteins and other ligands and are essential for controlling cell polarity.
  • The complete description of lipid molecular species and their biological functions with regard to the expression of proteins involved in lipid metabolism and function, including gene regulation, is referred to as lipidomic.
  • Docosahexaenoic acid  is crucial for a baby's brain's growth and functional development. For adults' brains to continue functioning normally, DHA is also necessary. DHA deficiency is linked to learning difficulties, but consuming plenty of DHA in the diet boosts learning capacity.
  • Rods, cones, and intrinsically photosensitive retinal ganglion cells are the three types of photoreceptor cells that are now understood to exist in mammalian eyes.

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