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Cellular respiration is the mechanism through which eukaryotic cells obtain energy from organic molecules using oxygen. Cellular respiration occurs in both the cytoplasm and the mitochondria.

Cellular respiration is the process by which biological fuels are oxidized in the presence of an inorganic electron acceptor such as oxygen to generate large amounts of energy, which is then used to drive the bulk production of ATP. The cytosol is responsible for glycolysis, whereas the mitochondrion is responsible for pyruvate oxidation, the Krebs cycle, and oxidative phosphorylation.

Carbon dioxide, ATP, and water are the byproducts of cellular respiration. Two carbon dioxide are produced during the synthesis of acetyl-CoA from pyruvate. During the Krebs cycle, four extra carbon dioxide molecules are generated. This carbon dioxide is carried to the bloodstream and ultimately to the lungs.

Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen) (without oxygen). During aerobic cellular respiration, glucose combines with oxygen to generate ATP, which the cell may utilise. As a byproduct, carbon dioxide and water are produced.

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