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Temporal bone is developed by endochondral ossification.

Endochondral ossification is one of two essential processes that produce bone tissue during fetal development of the mammalian skeletal system. Unlike intramembranous ossification, the other process by which bone tissue is produced, endochondral ossification involves the presence of cartilage.

This procedure involves replacing hyaline cartilage with bone. It begins with the differentiation of mesoderm-derived mesenchymal cells into chondrocytes. Chondrocytes proliferate quickly and secrete an extracellular matrix to form the bone cartilage model.

This is the most common way for bones to form. The femur, tibia, vertebrae, and metacarpals are some examples. The process begins in ossification centers in the embryonic skeleton and continues into the late adolescent years.

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