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Concordance Rates for schizophrenia are 50% for monozygotic twins and 18% for dizygotic twins.
Concordance Rate : A percentage that exhibit a particular trait or disorder among pairs of family members. It range from 0% to 100%. The higher the concordance rate, the more similar pairs of persons are within a sample.
Concordance Rates for schizophrenia are 50% for monozygotic twins and 18% for dizygotic twins. This means that when one monozygotic twin has schizophrenia, 50% of the time the other twin has schizophrenia as well. For dizygotic twins, when one twin has schizophrenia, the other twin has the disorder only 18% of the time.
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According to the functional connectivity of 48% for MZ twins & 4% for DZ twins, DSM-III-R schizophrenia is inherited genetically.
Which pair of twins, monozygotic (mz) or dizygotic (dz), had schizophrenia concordance rates that were higher?
The concordance rates for schizophrenia in monozygotic (identical) twins (MZ) are considerably greater than those in dizygotic (fraternal) twins (DZ). Distinguishing genetic influences from environmental impacts is a difficult task in these investigations. In certain cases, schizophrenia can result in brain damage.
According to research showing a significant degree of heritability in families, twin concordance, and adoption, schizophrenia is thought to have a sizable genetic component. According to reports, the concordance rates between monozygotic and dizygotic twins are, respectively, 10% to 15% and up to 50%. (Kringlen, 2000).
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