How does gene expression differ between human fibroblasts and induced pluripotent stem cells?

Gene expression is basically a process in which information from a gene is used in the synthesis of a functional gene product but human fibroblasts and induced pluripotent are different types of cells where they are from human body but induced pluripotent are stem cells which can be generated directly from adult cells.

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adioabiola adioabiola · Answer 2 · 2022-01-10T12:07:19+01:00

How gene expression differ between human fibroblasts and induced pluripotent stem cells.

First and foremost, gene expression is the process by which a gene gets turned on in a cell to make RNA and proteins. This expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Induced pluripotent stem cells (iPSCs) are generated through a gradual process in which somatic cells undergo a number of stochastic events.

Differentiated cells can be reprogrammed to pluripotent cells through viral introduction of the four transcription factors Oct4, Sox2, Klf4, and c-Myc

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